FORMULASI KRIM DARI EKSTRAK AIR DAUN ALPUKAT (Persea americana Mill.) SEBAGAI SEDIAAN ANTI JERAWAT

  • Wilda Wildani Stifar
  • nofriyanti nofriyanti
Keywords: Acne, antibacterial activity, avocado leaves, cream, Staphylococcus aureus

Abstract

Acne is a common skin condition in the community. Inflammation of acne can be caused by the bacteria Propionibacterium acne, Staphylococcus epidermidis, Staphylococcus aureus. Cream is a form of acne preparations that circulate on the market, usually cream contains various chemicals, one of the side effects can irritate the skin, thus it is necessary to solution the use of materials from plants that are as antibacterial. One of the herbs that have been scientifically proven to contain antibacterial agents and that can be used to treat acne is Avocado leaves (Persea americana Mill.). This study aims to form the water extract of avocado leaf (Persea americana Mill.) To be formulated in a stable anti-acne cream preparation and can inhibit the bacteria Staphylococcus aureus. Formulation of avocado leaves water extract cream was made at concentrations of 12.5%, 15%, 17.5%, 20%. The results of this study indicate that the cream of avocado leaves water extract is good and physically stable for 4 weeks of storage, and is effective as an anti-acne. It is expected that this study will provide information that the natural ingredients of avocado leaves can inhibit the bacteria Staphylococcus aureus as the cause of acne bacteria.

Author Biography

nofriyanti nofriyanti

Anief, M. 1997. Formulasi Obat Topikal Dengan Dasar Penyakit Kulit. Yogyakarta: Gajah Mada University Press.
Anonim. 1987. Formularium Medicamentum Selectum. Surabaya: Ikatan Sardjana Farmasi Indonesia
Anonim. 1995. Farmakope Indonesia Edisi Keempat. Jakarta: Depertemen Kesehatan RI.
Dalimartha, S. 2008. Atlas Tumbuhan Obat Indonesia Jilid 5. Jakarta: Pustaka Bunda.
Davis & Stout. (1971). Disc Plate Method Of Microbiological Antibiotic Essay. Journal Of Microbiology. 22 (4): 659-665.
Harahap, M. 2000. Ilmu Penyakit Kulit. Jakarta: Buku Kedokteran EGC.
Jelinek, S.J, 1970, Formularium and Function of Cosmetic, willey interscienci, New York, London.
Mardiyaningsih,A. dan Nur Ismiyati. 2014. “Cytotoxic Activity Of Ethanolic Extract Of Persea Americana Mill . Leaves On Hela Cervical Cancer Cell.” Tradisional Medicine Journal 19(1):24–28.
Martin A.J.S., Swarbrick, dan A. Cammarata, 1993., Farmasi Fisika, Edisi III diterjemahkan oleh Yoshita Universitas Indonesia.
Riska,C.A, Frida.O, Risa.N, 2016. "Uji Zona Hambat Ekstrak Etil Asetat Daun Alpukat (Persea Americana Mill.) Terhadap Pertumbuhan Bakteri Staphylococcus Aureus." Jurnal Kedokteran Syiah Kuala 16(1):1-5.
Syamsul, E.S, Supomo., Heri.W., dan Bramantyo.A.N. 2015. “Formulasi Ekstrak Etanol Umbi Bawang Tiwai (Eleutherine Americana) Dalam Sediaan Krim Anti Acne.” Tradisional Medicine Journal 20(September):149–57.
Wisitaatmadja, S.M. 1997. Penuntun Ilmu Kosmetik Medik. Jakarta : Universitas Indonesia.
Widodo, H. 2013. Ilmu Meracik Obat Untuk Apoteker. Yogyakarta: D- Medika.
Voight. R, 1994, Buku Pelajaran Teknologi Farmasi, Yogyakarta: Gadjah Mada University Press.

 

References

Anief, M. 1997. Formulasi Obat Topikal Dengan Dasar Penyakit Kulit. Yogyakarta: Gajah Mada University Press.
Anonim. 1987. Formularium Medicamentum Selectum. Surabaya: Ikatan Sardjana Farmasi Indonesia
Anonim. 1995. Farmakope Indonesia Edisi Keempat. Jakarta: Depertemen Kesehatan RI.
Dalimartha, S. 2008. Atlas Tumbuhan Obat Indonesia Jilid 5. Jakarta: Pustaka Bunda.
Davis & Stout. (1971). Disc Plate Method Of Microbiological Antibiotic Essay. Journal Of Microbiology. 22 (4): 659-665.
Harahap, M. 2000. Ilmu Penyakit Kulit. Jakarta: Buku Kedokteran EGC.
Jelinek, S.J, 1970, Formularium and Function of Cosmetic, willey interscienci, New York, London.
Mardiyaningsih,A. dan Nur Ismiyati. 2014. “Cytotoxic Activity Of Ethanolic Extract Of Persea Americana Mill . Leaves On Hela Cervical Cancer Cell.” Tradisional Medicine Journal 19(1):24–28.
Martin A.J.S., Swarbrick, dan A. Cammarata, 1993., Farmasi Fisika, Edisi III diterjemahkan oleh Yoshita Universitas Indonesia.
Riska,C.A, Frida.O, Risa.N, 2016. "Uji Zona Hambat Ekstrak Etil Asetat Daun Alpukat (Persea Americana Mill.) Terhadap Pertumbuhan Bakteri Staphylococcus Aureus." Jurnal Kedokteran Syiah Kuala 16(1):1-5.
Syamsul, E.S, Supomo., Heri.W., dan Bramantyo.A.N. 2015. “Formulasi Ekstrak Etanol Umbi Bawang Tiwai (Eleutherine Americana) Dalam Sediaan Krim Anti Acne.” Tradisional Medicine Journal 20(September):149–57.
Wisitaatmadja, S.M. 1997. Penuntun Ilmu Kosmetik Medik. Jakarta : Universitas Indonesia.
Widodo, H. 2013. Ilmu Meracik Obat Untuk Apoteker. Yogyakarta: D- Medika.
Voight. R, 1994, Buku Pelajaran Teknologi Farmasi, Yogyakarta: Gadjah Mada University Press.
Published
2019-05-01
Section
Articles