SUMBER POTENSIAL AGEN ANTIINFLAMASI TANAMAN INDONESIA DARI USADA TARU PREMANA DAN PERKEMBANGAN FORMULASINYA: TELAAH PUSTAKA
DOI:
https://doi.org/10.51887/jpfi.v13i1.1901Keywords:
Herbal, ekstrak, tanaman obat, inflamasi, usada taru premanaAbstract
Peradangan atau inflamasi merupakan salah satu respon tubuh terhadap kerusakan jaringan, kontak dengan zat asing, respon imun, maupun salah satu akibat dari trauma fisik. Inflamasi merupakan gejala umum yang sering terjadi pada beberapa penyakit. Penggunaan obat antiinflmasi steroid dan non-steroid merupakan alternatif yang umum digunakan, akan tetapi penggunaannya diketahui menimbulkan efek samping merugikan bagi tubuh. Hal ini mendorong banyak penelitian mengenai pengobatan alternatif lain dari tumbuhan obat. Salah satu contoh yang menarik dibahas yaitu tanaman tradisional khas Bali yang tertulis dalam Usada Taru Premana (naskah medis kuno yang ada di Bali). Pada artikel ini akan dibahas mengenai rangkuman beberapa tanaman khas Bali yang terbukti khasiatnya sebagai agen anti-inflamasi melalui pengujian in vitro dan in vivo. Penelitian ini menggunakan studi literatur yang mengumpulkan data dan informasi dari mesin pencarian seperti PubMed, Google Cendekia dengan kata kunci (herbal, ekstrak, tanaman obat, inflamasi, taru premana) atau dan basis data ilmiah. Hasil studi literatur menunjukkan bahwa beberapa tanaman yang tercantum di dalam Usada Taru Premana berpotensi untuk dikembangkan menjadi agen antiinflamasi sebagai alternatif penggunaan obat antiinflamasi sintetis.
Inflammation is one of the body's responses to tissue damage, exposure to foreign substances, immune responses, or a result of physical trauma. It's a common symptom in several diseases. The use of anti-inflammatory drugs, both steroid and non-steroid, is a commonly employed alternative, but their usage is known to cause harmful side effects to the body. This has spurred many studies on alternative herbal treatments. An interesting example discussed is the distinctive traditional plants from Bali as documented in the Usada Taru Premana (an ancient medical manuscript found in Bali).. This article will cover a summary of several typical Balinese plants proven to have anti-inflammatory properties through in vitro and in vivo testing. This study utilizes a literature review collecting data and information from search engines like PubMed, Google Scholar, using keywords (herbal, extract, medicinal plants, inflammation, taru premana), and scientific databases. The results of the literature study indicate that several plants listed in Usada Taru Premana have the potential to be developed into anti-inflammatory agents as an alternative to the use of synthetic anti-inflammatory drugs.
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